Thermo Fisher Scientific GBA Polyclonal Antibody
인간 GBA 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제됨. PBS/glycerol 완충액에 보관되며 장기 저장은 -20°C 권장. 연구용 전용 시약.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein of human Glucosylceramidase beta (GBA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2803813 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
GBA encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism.
Mutations in this gene cause Gaucher disease, a lysosomal storage disorder characterized by accumulation of glucocerebrosides.
A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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