Thermo Fisher Scientific RNF169 Polyclonal Antibody
Human RNF169 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 Immunoprecipitation에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 1 mg/mL 농도의 액상 제품. DNA 손상 복구 연구용으로 적합.
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Applications
Western Blot (WB)
- Assay-dependent
Immunoprecipitation (IP)
- 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 200 to 250 of Human Ring Finger Protein 169 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
Probable E3 ubiquitin-protein ligase that acts as a negative regulator of double-strand breaks (DSBs) repair following DNA damage.
Recruited to DSB repair sites by recognizing and binding ubiquitin catalyzed by RNF168, and competes with TP53BP1 and BRCA1 for association with RNF168-modified chromatin, thereby acting as a negative regulator of DSBs repair.
E3 ubiquitin-protein ligase activity is not required for regulation of DSBs repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(원본 이미지 파일명: A304-097A_RNF169_Q8NCN4-1_Rabbit.svg, A304-097A_RNF169_Q8NCN4-1_Rabbit_PDP.jpeg)
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