Thermo Fisher Scientific RGS1 Polyclonal Antibody, MaxPab

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG

Class

Polyclonal

Type

Antibody

Immunogen

RGS1 (AAH15510.1, 1 a.a. approximately 196 a.a) full-length human protein.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Product may be used with Western Blot (Transfected lysate).

The Isotype of this product is composed of an IgG Mixture.

Immunogen sequence: MPGMFFSANP KELKGTTHSL LDDKMQKRRP KTFGMDMKAY LRSMIPHLES GMKSSKSKDV LSAAEVMQWS QSLEKLLANQ TGQNVFGSFL KSEFSEENIE FWLACEDYKK TESDLLPCKA EEIYKAFVHS DAAKQINIDF RTRESTAKKI KAPTPTCFDE AQKVIYTLME KDSYPRFLKS DIYLNLLNDL QANSLK

Target Information

This gene encodes a member of the regulator of G-protein signaling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.