Thermo Fisher Scientific KIRREL Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 17-200 of human KIRREL (NP_0607103) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:KIRREL,uniProtId:Q96J84-1,ncbiNodeId:9606,antigenRange:17-200,antigenLength:757,antigenImageFileName:PA5-89723_KIRREL_Q96J84-1_Rabbit.svg,antigenImageFileNamePDP:PA5-89723_KIRREL_Q96J84-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.85 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805745

Product Specific Information

Immunogen sequence: QGTQTRFSQE PADQTVVAGQ RAVLPCVLLN YSGIVQWTKD GLALGMGQGL KAWPRYRVVG SADAGQYNLE ITDAELSDDA SYECQATEAA LRSRRAKLTV LIPPEDTRID GGPVILLQAG TPHNLTCRAF NAKPAATIIW FRDGTQQEGA VASTELLKDG KRETTVSQLL INPTDLDIGR VFTC; Positive Samples: Mouse kidney, Mouse lung; Cellular Location: Cell membrane, Single-pass type I membrane protein

Target Information

KIRREL (NEPH1) is a member of the nephrin-like protein family, which includes NEPH2 and NEPH3. The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. NEPH1 is a member of the nephrin-like protein family, which includes NEPH2. The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003).

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.