Thermo Fisher Scientific Phospho-AANAT (Thr29) Polyclonal Antibody
Rat 조직에서 phospho-AANAT(Thr29)을 검출하는 Rabbit Polyclonal Antibody. Western blot에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제됨. PBS/BSA 버퍼에 보관하며 -20°C에서 안정적. 멜라토닌 합성 연구용으로 적합.
- 카탈로그번호
- PA1761
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-AANAT (Thr29) Polyclonal Antibody
Thermo Fisher Scientific Phospho-AANAT (Thr29) Polyclonal Antibody
Applications
- Western Blot (WB): 0.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic Peptide: C(24) Q R R H T(p) L P A S(33) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2273327 |
Product Specific Information
PA1-761 detects phospho serotonin N-acetyltransferase (AA-NAT) from rat tissues.
PA1-761 has been successfully used in Western blot procedures.
By Western blot, this antibody detects an ~23 kDa protein representing phospho AA-NAT in rat pineal gland whole protein extract.
The immunizing phosphopeptide (Cat. # PEP-064) corresponds to amino-terminal amino acid residues 24–33 of mouse AA-NAT.
Total anti-amino-terminal AA-NAT-specific IgG (Cat. # PA1-760) was affinity purified on resin-coupled non-phosphopeptide (Cat. # PEP-063).
Phospho-specific amino-terminal IgG (Cat. # PA1-761) was subsequently isolated on resin-coupled phosphopeptide (Cat. # PEP-064).
This sequence is completely conserved between mouse, rat, and human AA-NAT protein.
Target Information
Arylalkylamine N-Acetyltransferase (AANAT) is the penultimate enzyme in melatonin synthesis.
Melatonin plays a key role in sleep and circadian rhythm regulation.
Large changes in AANAT abundance are responsible for day/night rhythms in melatonin synthesis in the pineal gland and retina.
AANAT activity is mainly regulated by controlling steady-state protein levels, but additional mechanisms may contribute to rapid melatonin production at the onset of darkness in humans.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.