Thermo Fisher Scientific TIA-1 Monoclonal Antibody (3A3B9)
Western blot, IHC, ICC/IF, Flow Cytometry 등 다양한 응용에 적합한 TIA-1 단클론 항체. Human 시료 반응성, Mouse IgG1 아이소타입. Protein G 정제, 1 mg/mL 농도의 액상 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장.
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3A3B9 |
| Immunogen | Purified recombinant fragment of human TIA1 (aa 1–215) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898554 |
Product Specific Information
This antibody has been tested in indirect ELISA.
Target Information
Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from:
- A WNT protein (WNT3A) to stabilize beta-catenin
- Noggin, which is a bone morphogenetic protein inhibitor
Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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