Thermo Fisher Scientific KIRREL2 Monoclonal Antibody (318311)
KIRREL2 단백질을 인식하는 마우스 단클론 항체로, Western blot에 최적화되어 있습니다. 인간 및 생쥐 시료에서 반응하며, 단백질 A/G로 정제된 고순도 제품입니다. 동결건조 형태로 제공되며, 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): Tested dilution 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 318311 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human Kirrel2 (Gly21–Arg503) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2607204 |
Product Specific Information
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
The KIRREL2 gene encodes a type I transmembrane protein, a member of the immunoglobulin superfamily of cell adhesion molecules. The protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against this protein have been detected in serum from patients with type 1 diabetes. It may also play a role in glomerular development, with decreased expression observed in glomerular diseases. This gene and the opposite-strand gene nephrin are regulated by a bidirectional promoter.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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