Thermo Fisher Scientific Phospho-ATF4 (Ser245) Polyclonal Antibody
Phospho-ATF4 (Ser245) 폴리클로날 항체로 인간 시료에 반응하며 Western blot 및 IHC에 사용 가능. Ser245 인산화 부위를 포함한 펩타이드 면역원으로 제작. Protein A로 정제된 액상 항체이며 -20°C에서 보관. 연구용으로만 사용.
- 카탈로그번호
- 43053-100UL
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunohistochemistry (IHC)
- Tested Dilution: 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence that includes phosphorylation sites of Serine 245 (N-R-S(p)-L-P) derived from human ATF4 and conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | Dulbecco’s PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein capable of binding a tax-responsive enhancer element in the LTR of HTLV-1. It was also characterized as the cAMP-response element binding protein 2 (CREB-2).
The encoded protein belongs to a family of DNA-binding proteins including the AP-1 family, CREBs, and CREB-like proteins. These transcription factors share a leucine zipper region involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids functioning as a DNA binding domain.
Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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