Thermo Fisher Scientific Phospho-P95/NBS1 (Ser343) Polyclonal Antibody
인간 p95/NBS1 단백질의 Ser343 인산화 부위를 인식하는 Rabbit Polyclonal 항체. Western blot에 적합하며, 단백질 손상 복구 및 세포 주기 연구에 활용 가능. Protein A로 정제된 액상 형태로, -20°C에서 보관.
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Applications
- Western Blot (WB): 1:500–1:1,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence including phosphorylation site of Serine 343 (S-L-S(p)-Q-G) derived from human p95/NBS1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | Dulbecco’s PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The p95 gene (identical to NBS1 and nibrin) is part of the hMre11/hRad50 double-strand break complex. This complex is implicated in Nijmegen breakage syndrome, an autosomal recessive disorder characterized by increased cancer incidence, cell cycle checkpoint defects, and ionizing radiation sensitivity. It provides a molecular link between double-strand break repair and cell cycle checkpoint regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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