Thermo Fisher Scientific EXOSC5 Polyclonal Antibody

Thermo Fisher Scientific EXOSC5 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

Immunogen sequence:
MEEETHTDAK IRAENGTGSS PRGPGCSLRH FACEQNLLSR PDGSASFLQG DTSVLAGVYG PAEVKVSKEI FNKATLEVIL RPKIGLPGVA EKSRERLIRN TCEAVVLGTL HPRTSITVVL QVVSDAGSLL ACCLNAACMA LVDAGVPMRA LFCGVACALD SDGTLVLDPT SKQEKEARAV LTFALDSVER KLLMSSTKGL YSDTELQQCL AAAQAASQHV FRFYRESLQR RYSKS

Target Information

Non-catalytic component of the RNA exosome complex which has 3′→5′ exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events.
In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA, and snoRNA, and in the elimination of RNA processing by-products and non-coding transcripts.
In the cytoplasm, the RNA exosome complex contributes to general mRNA turnover and RNA surveillance pathways, preventing translation of aberrant mRNAs.
It may also be involved in degradation of histone mRNA.
The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) serves as a scaffold for association with catalytic subunits and accessory proteins.
[UniProt]

Safety Information

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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