Thermo Fisher Scientific F5 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 300-510 of human F5 (NP_000121.2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Factor V,uniProtId:P12259-1,ncbiNodeId:9606,antigenRange:300-510,antigenLength:2224,antigenImageFileName:PA5-109702_Factor_V_P12259-1_Rabbit.svg,antigenImageFileNamePDP:PA5-109702_Factor_V_P12259-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.84 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2855113

Product Specific Information

Immunogen sequence: VGPEGKWIIS SLTPKHLQAG MQAYIDIKNC PKKTRNLKKI TREQRRHMKR WEYFIAAEEV IWDYAPVIPA NMDKKYRSQH LDNFSNQIGK HYKKVMYTQY EDESFTKHTV NPNMKEDGIL GPIIRAQVRD TLKIVFKNMA SRPYSIYPHG VTFSPYEDEV NSSFTSGRNN TMIRAVQPGE TYTYKWNILE FDEPTENDAQ CLTRPYYSDV D

Target Information

Coagulation factor V (or Proaccelerin) is an essential factor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The active factor V is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in the Factor V gene can result various diseases including Factor V deficiency, thrombophilia due to activated protein C resistance, Budd-Chiari syndrome, Ischemic stroke, and recurrent pregnancy loss.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.