
Thermo Fisher Scientific APOBR Monoclonal Antibody (OTI1B5), TrueMAB
Human APOBR 단백질을 인식하는 마우스 단일클론 항체로 Western Blot 및 IHC(Paraffin)에 적합. 비결합형, 동결건조 형태이며 PBS 버퍼에 trehalose 포함. 고순도 친화 크로마토그래피 정제. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 780–1088 of human APOBR produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Macrophage receptor that binds to apolipoprotein B48 (APOB) of dietary triglyceride-rich lipoproteins (TRL) or similar domains in hypertriglyceridemic very low-density lipoprotein (HTG-VLDL).
Functions include:
- Binding and internalizing TRL outside macrophage context
- Providing essential lipids to reticuloendothelial cells
- Possible involvement in foam cell formation with elevated TRL and remnant lipoprotein (RLP)
- Mediates rapid, high-affinity uptake of chylomicrons (CM), HTG-VLDL, and trypsinized VLDL devoid of APOE in vitro in macrophages
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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