Thermo Fisher Scientific NSE2 Monoclonal Antibody (OTI6A6)
NSE2 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot, ICC/IF, Flow Cytometry에 사용 가능. Mouse IgG2a 형식이며, 고순도의 액상 형태로 제공. 인간 단백질에 반응하며, PBS 기반 보존 용액에 포함되어 안정적.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6A6 |
| Immunogen | Full length human recombinant protein of NSMCE2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.52 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724875 |
Target Information
This gene encodes the large subunit of DNA damage-binding protein, which is a heterodimer composed of a large and a small subunit. This protein functions in nucleotide-excision repair. Defective activity causes repair defects in patients with xeroderma pigmentosum complementation group E (XPE). Mutation analysis is required to determine whether the defect in XPE patients is in this gene or the gene encoding the small subunit. Additionally, Best vitelliform macular dystrophy is mapped to the same region (11q), but no sequence alterations of this gene are demonstrated in Best disease patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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