Thermo Fisher Scientific NSE2 Monoclonal Antibody (OTI4A2)
Human NSE2 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot, ICC/IF, Flow cytometry에 적합합니다. 1 mg/mL 농도의 액상 형태이며, PBS/BSA/glycerol buffer로 안정화되어 있습니다. 연구용으로 DNA 손상 복구 관련 단백질 분석에 활용됩니다.
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Applications 및 Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4A2 |
| Immunogen | Full length human recombinant protein of NSMCE2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724874 |
Target Information
This gene encodes the large subunit of DNA damage-binding protein, which forms a heterodimer with a small subunit and functions in nucleotide-excision repair. Defective activity of this protein is associated with xeroderma pigmentosum complementation group E (XPE). Mutation analysis is required to confirm whether the defect in XPE patients lies in this gene or in the gene encoding the small subunit. Additionally, Best vitelliform macular dystrophy is mapped to the same region (11q), though no sequence alterations of this gene are found in Best disease patients.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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