Thermo Fisher Scientific Cyr61 Polyclonal Antibody
Thermo Fisher Scientific의 Cyr61 Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하며 Western blot 및 ELISA에 적합합니다. KLH 결합 합성 펩타이드로 면역화된 Rabbit IgG 항체로, 단백질 A로 정제되었으며 -20°C에서 보관합니다. 연구용 전용 제품입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Cyr61, amino acids 251–379 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CYR61 is a secreted heparin-binding protein encoded by a growth factor-inducible immediate-early gene. It associates with the extracellular matrix and connective tissue.
CYR61 belongs to the CCN protein family, which includes connective tissue growth factor (CTGF) and the mouse CYR61 homolog Fisp12.
As an angiogenic inducer, CYR61 binds to the cell surface receptor integrin αvβ3, stimulating cell adhesion, migration, and DNA synthesis in human vascular endothelial cells.
Expression of CYR61 increases during vessel growth, wound healing, and chondrocyte differentiation, and it is detected in various tumors as a marker of tumor progression.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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