Thermo Fisher Scientific Phospho-c-Fos (Ser362) Polyclonal Antibody
Phospho-c-Fos (Ser362) 폴리클로날 항체로 인간, 마우스, 랫트 시료에 반응. WB, IHC, ICC, ELISA 등 다양한 응용 가능. Protein A 정제된 액상 형태로 1 mg/mL 농도. 세포 신호전달 및 인산화 연구에 적합.
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Thermo Fisher Scientific Phospho-c-Fos (Ser362) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic phosphopeptide derived from human c-Fos around the phosphorylation site of Ser362 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
FBJ murine osteosarcoma viral oncogene homolog, commonly known as Cellular protooncogene Fos (c-Fos), belongs to the fos transcription factor family and is encoded by the C-FOS gene located on chromosome 14.
c-Fos heterodimerizes with c-Jun to form the Activator Protein-1 (AP-1) transcription factor, which regulates transcription of several genes involved in cellular signal transduction, proliferation, and differentiation.
c-Fos phosphorylation occurs at multiple sites in response to stimuli such as growth factors and insulin. The ERK MAPK kinase phosphorylates c-Fos at Threonine 232, influencing its nuclear localization and transcriptional activity.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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