Thermo Fisher Scientific GRAP Polyclonal Antibody
GRAP 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 사용 가능. 인간, 생쥐, 비인간 영장류에 반응하며, 고순도의 Affinity Chromatography 정제 제품. PBS/glycerol buffer에 보관, 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GRAP (Accession Q13588), corresponding to amino acid residues I185–L217 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | –20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2818565 |
Product Specific Information
Antibody detects endogenous levels of total GRAP.
Target Information
This gene encodes a member of the GRB2/Sem5/Drk family. The protein functions as a cytoplasmic signaling molecule containing an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, facilitating the formation of a stable complex with the BCR-ABL oncoprotein. It also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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