Thermo Fisher Scientific GRB10 Polyclonal Antibody
인간 GRB10 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 Immunocytochemistry에 사용 가능. 합성 펩타이드 항원을 기반으로 제작되었으며, 액상 형태로 1 mg/mL 농도. PBS와 50% 글리세롤 버퍼에 보관하며 -20°C에서 안정적으로 저장 가능.
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- PA599633
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
- Publications: 없음
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
- Publications: 없음
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GRB10 (Accession Q13322), corresponding to amino acid residues N406–L456 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2818566 |
Product Specific Information
Antibody detects endogenous levels of total GRB10.
Target Information
GRB7, a SH2 domain protein, has a single SH2 domain at its C-terminal, a central region with similarity to Ras GAP, and a proline-rich N terminus.
A related SH2 domain-containing protein, GRB10, exhibits a high degree of homology with GRB7.
GRB10 undergoes serine but not tyrosine phosphorylation in response to EGF treatment, but appears to bind to the EGF receptor poorly.
GRB10 maps to mouse chromosome 11, in close proximity to the EGF receptor. Similarly, GRB7 maps to the same mouse chromosome near the EGF receptor-related protein HER2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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