Thermo Fisher Scientific Granzyme H Polyclonal Antibody
Granzyme H 단백질을 인식하는 Rabbit Polyclonal 항체로, Human 및 Mouse 시료에 반응합니다. Western blot, IHC, ICC/IF에 사용 가능하며, 고순도 Affinity chromatography로 정제되었습니다. PBS/glycerol buffer에 보관되며 연구용으로 적합합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GZMH (Accession P20718), corresponding to amino acid residues R55–F105 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818564 |
Product Specific Information
Antibody detects endogenous levels of total Granzyme H.
Target Information
This gene encodes a member of the peptidase S1 family of serine proteases.
Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a chymotrypsin-like protease.
This protein is reported to be constitutively expressed in the NK (natural killer) cells of the immune system and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells.
This gene is present in a gene cluster with another member of the granzyme subfamily on chromosome 14.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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