Thermo Fisher Scientific RYR3 Polyclonal Antibody
RYR3 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 IHC에 적합하며, 인간 단백질에 반응. 동결건조 형태로 제공되며, 장기 보관 시 -20°C 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the C-terminal region of human Ryanodine receptor 3 (RYR3) conjugated to a blue carrier protein was used as the antigen. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C for short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: RYR3
Target Information
RYR3 is a ryanodine receptor that releases calcium from intracellular storage for use in various cellular processes. It plays a critical role in skeletal muscle contraction by releasing calcium from the sarcoplasmic reticulum upon T-tubule depolarization.
Two transcript variants encoding different isoforms of RYR3 have been identified.
RYR3 mediates calcium release into the cytoplasm, contributing to muscle contraction and cellular calcium ion homeostasis. It may also regulate calcium release from the endoplasmic reticulum in non-muscle cells.
Diseases associated with RYR3 include Central Core Disease and Arrhythmogenic Right Ventricular Dysplasia 2.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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