Thermo Fisher Scientific Phospho-CaMKI (Thr177) Polyclonal Antibody
Phospho-CaMKI (Thr177) 폴리클로날 항체로, 인산화된 CaMK1α를 특이적으로 검출합니다. Western blot과 IHC(파라핀 절편)에 적합하며, 사람, 마우스, 랫트 시료에 반응합니다. PBS/glycerol 용액 형태로 제공되며, -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CAMK1 (Accession Q14012), corresponding to amino acid residues around phosphorylated Thr177 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2817072 |
Product Specific Information
This antibody detects endogenous levels of CaMK1 alpha only when phosphorylated at Thr177.
Target Information
CAMK1 (CaMK1) is a serine/threonine kinase belonging to the calcium/calmodulin-dependent protein kinase family. It plays roles in cell differentiation, nervous system development, and signal transduction. CAMK1 is expressed in many tissues and functions as part of a calmodulin-dependent kinase cascade. Calcium/calmodulin directly activates CaMK1 by binding to the enzyme and indirectly enhances its phosphorylation and activation through CaMK1 kinase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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