Thermo Fisher Scientific S100A12 Polyclonal Antibody
Human S100A12 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC 및 ELISA에 사용 가능. Preservative-free 제형으로 오염 방지를 위해 sodium azide 추가 권장. 세포 신호전달 및 염증 연구용으로 적합.
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Thermo Fisher Scientific S100A12 Polyclonal Antibody
Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:2,500–1:10,000
- ELISA: 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human S100A12 protein (UniProt ID: P80511-1, Range: 1–92) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | No preservative |
| Storage conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788242 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human S100A12/CAGC.
Target Information
S100A12 is a member of the S100 family of proteins containing two EF-hand calcium-binding motifs. These proteins are found in the cytoplasm and/or nucleus of various cell types and are involved in regulation of cellular processes such as cell cycle progression and differentiation.
S100A12 is proposed to participate in calcium-dependent signal transduction pathways and regulate cytoskeletal components affecting neutrophil activity. It also acts as a ligand for RAGE, triggering cellular activation and inflammatory responses through NF-κB activation. Additionally, S100A12 exhibits anti-microbial properties.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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