Thermo Fisher Scientific ATP5C1 Monoclonal Antibody (OTI2H6), TrueMAB

Applications

• Western Blot (WB): 1:2,000
• Immunohistochemistry (Paraffin) (IHC (P)): 1:150

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation.
ATP synthase consists of two linked multi-subunit complexes: the soluble catalytic core (F1) and the membrane-spanning component (Fo), which forms the proton channel.
The catalytic portion includes five different subunits (alpha, beta, gamma, delta, epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and one each of the other three.
The proton channel consists of three main subunits (a, b, c). This gene encodes the gamma subunit of the catalytic core.
Alternatively spliced transcript variants encoding different isoforms have been identified, and a pseudogene exists on chromosome 14.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.