Thermo Fisher Scientific CD11c Monoclonal Antibody (3.9), FITC, eBioscience
인간 CD11c를 인식하는 단클론 항체로, FITC 형광 표지되어 Flow Cytometry 분석에 최적화됨. 3.9 클론, Mouse IgG1 kappa 아이소타입. 인간 및 마우스 반응성. 4°C 암소 보관, 동결 금지. 연구용으로만 사용.
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Thermo Fisher Scientific CD11c Monoclonal Antibody (3.9), FITC, eBioscience™
Applications and Tested Dilution
- Application: Flow Cytometry (Flow)
- Tested Dilution: 5 µL (1 µg)/test
- Publications: View 28 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), FITC, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3.9 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 5 µL/test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11150063 |
Available Formats
- Unconjugated
- Alexa Fluor 532
- Alexa Fluor 700
- APC
- APC-eFluor 780
- Biotin
- Brilliant UV 737
- Brilliant UV 805
- eFluor 450
- eFluor 506
- PE
- PE-Cyanine5
- PE-Cyanine5.5
- PE-Cyanine7
- PE-eFluor 610
- PerCP-eFluor 710
- Super Bright 600
- Super Bright 645
- Super Bright 702
- Super Bright 780
- Request custom conjugation
Product Specific Information
Description:
The 3.9 monoclonal antibody reacts with human CD11c, the 150 kDa integrin alpha X chain. CD11c non-covalently associates with beta2 integrin to form the CD11c/CD18 heterodimer. This complex is expressed on monocytes, granulocytes, macrophages, NK cells, dendritic cells, and subsets of T and B lymphocytes. CD11c/CD18 binds to CD54, iC3b, and fibrinogen, playing a role in leukocyte adhesive interactions.
Applications Reported:
The 3.9 antibody has been reported for use in flow cytometric analysis.
Applications Tested:
Pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. Use at 5 µL (1 µg) per test. A test is defined as the amount of antibody that stains a cell sample in a final volume of 100 µL. Cell number may range from 10⁵ to 10⁸ cells/test.
Excitation: 488 nm
Emission: 520 nm
Laser: Blue Laser
Filtration: 0.2 µm post-manufacturing filtered
Target Information
CD11, along with CD18, forms a heterodimer adhesion molecule. CD11 is composed of CD11a, CD11b, and CD11c.
- CD11a: Expressed in B and T lymphocytes, macrophages, monocytes, neutrophils, basophils, and eosinophils
- CD11b: Expressed by monocytes, macrophages, NK cells, some B and T cells, and granulocytes
- CD11c: Expressed in monocytes, macrophages, NK cells, some granulocytes, and a subset of lymphocytes
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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