
Thermo Fisher Scientific IRS-2 Polyclonal Antibody
IRS-2 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 응용에 적합합니다. 인간, 마우스, 랫트 반응성을 가지며, 항원 친화 크로마토그래피로 정제되었습니다. 세포질 내 IRS-2 신호전달 연구용으로 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the epitope ASSPA without phosphorylation site Ser 731 of human IRS-2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Human kidney
- Cellular location: Cytoplasm
Target Information
The IRS2 (Insulin Receptor Substrate 2) gene encodes a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1 (IGF1), and other cytokines. It acts as a molecular adaptor between receptor tyrosine kinases and downstream effectors. The IRS-2 protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, and also by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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