Thermo Fisher Scientific Human CRB2 Synthetic Peptide
인간 CRB2 단백질 중심부의 17개 아미노산 서열을 기반으로 한 합성 펩타이드. 항체 PA5-34492의 차단용 블로킹 펩타이드로 사용 가능. 고순도 정제, PBS 기반 액상 형태, 연구용으로 적합.
- 카탈로그번호
- PEP1534
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Human CRB2 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 17 amino acids near the center of human CRB2.
PEP-1534 can be used as a blocking peptide with polyclonal antibody PA5-34492.
Target Information
CRB2 (Crumbs homolog 2), like its homologs CRB1 and CRB3, is similar to the Drosophila crumbs protein and is expressed in retina, brain, and kidney.
Along with other proteins, the Crumbs proteins form a complex that helps establish cell polarity in developing neuroepithelial cells.
At the onset of neural specification, embryonic stem cells (ESCs) upregulate CRB2, which then localizes apically in neural rosettes.
Gain- and loss-of-function studies of CRB2 have shown that CRB2 is essential for the stabilization of other polarity proteins.
Unlike CRB1, mutations in CRB2 do not appear to play a role in retinitis pigmentosa or in Leber congenital amaurosis.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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