Thermo Fisher Scientific PRKAB2 Monoclonal Antibody (OTI4H4), TrueMAB
Human, Mouse, Rat에 반응하는 PRKAB2 단클론 항체로 Western blot에 적합. E.coli에서 생산된 full-length human PRKAB2 단백질을 면역원으로 사용. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능. 연구용으로만 사용.
- 카탈로그번호
- CF808333
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4H4 |
| Immunogen | Full length human recombinant protein of human PRKAB2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
AMPK Beta 2 is a regulatory subunit of the AMP-activated protein kinase (AMPK), a heterotrimeric enzyme consisting of alpha (catalytic), beta, and gamma (regulatory) subunits.
AMPK serves as a key energy sensor regulating cellular metabolism. Upon activation by metabolic stress, AMPK phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and HMG-CoA reductase (HMGCR), controlling fatty acid and cholesterol biosynthesis.
AMPK Beta 2 may positively regulate AMPK activity, and its myristoylation and phosphorylation influence enzyme activity and localization. It may also act as an adaptor mediating AMPK complex assembly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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