Thermo Fisher Scientific PRKAB2 Monoclonal Antibody (OTI4H4), TrueMAB

Applications

• Western Blot (WB): 1:2,000 dilution tested

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

AMPK Beta 2 is a regulatory subunit of the AMP-activated protein kinase (AMPK), a heterotrimeric enzyme consisting of alpha (catalytic), beta, and gamma (regulatory) subunits.
AMPK serves as a key energy sensor regulating cellular metabolism. Upon activation by metabolic stress, AMPK phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and HMG-CoA reductase (HMGCR), controlling fatty acid and cholesterol biosynthesis.
AMPK Beta 2 may positively regulate AMPK activity, and its myristoylation and phosphorylation influence enzyme activity and localization. It may also act as an adaptor mediating AMPK complex assembly.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.