Thermo Fisher Scientific TTLL12 Monoclonal Antibody (OTI1D3), TrueMAB
TTLL12 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot과 Flow cytometry에 최적화되어 있습니다. 인간 시료에 반응하며, 무보존제 PBS 버퍼에 동결건조 형태로 제공됩니다. 종양 연구 및 단백질 발현 분석에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D3 |
| Immunogen | Full length human recombinant protein of human TTLL12 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
TTLL12 (tubulin tyrosine ligase-like family, member 12) is a 644 amino acid protein containing one TTL domain.
Among the fourteen TTLL family members that modify tubulin, TTLL12 is the least characterized.
It is highly expressed in various metastatic prostate cancer cell lines and considered a potential tumor therapy target.
Overexpression may alter chromosome ploidy, while downregulation affects post-translational modifications of tubulin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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