
Thermo Fisher Scientific TTLL12 Monoclonal Antibody (OTI7F11), TrueMAB
TTLL12 단백질을 표적으로 하는 Mouse IgG1 단클론 항체로, Western blot, IHC, ICC/IF, Flow cytometry에 적합합니다. HEK293T 세포에서 생산된 재조합 단백질을 면역원으로 사용하며, 고순도의 친화 크로마토그래피 정제 제품입니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific TTLL12 Monoclonal Antibody (OTI7F11), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Human, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7F11 |
| Immunogen | Full length human recombinant protein of human TTLL12 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended desalting tool: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
TTLL12 (tubulin tyrosine ligase-like family, member 12) is a 644-amino-acid protein containing one TTL domain.
Among the fourteen TTLL family members that modify tubulin, TTLL12 is the least characterized.
It is highly expressed in metastatic prostate cancer cell lines and considered a potential tumor therapy target.
Overexpression of TTLL12 may alter chromosome ploidy, while downregulation influences tubulin post-translational modifications.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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