Thermo Fisher Scientific IFNAR1 Polyclonal Antibody
인간 IFNAR1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. Western blot 및 Immunoprecipitation에 적합. 항원 친화 크로마토그래피로 정제된 액상 형태. 4°C에서 보관하며 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 507 to 557 of human Interferon (alpha, beta and omega) Receptor 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Interferons are widely used therapeutic agents because of their anti-tumor and antiviral effects and because of their modulatory effects on the immune system (Biron, 2001; Kirkwood, 2002).
These cytokines produce their effects by binding to the Type 1 Interferon Receptor (IFNAR1).
Downregulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling.
This downregulation is thought to be influenced by phosphorylation of Serine 535 and 539 in IFNAR1 (Kumar et al., 2003).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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