Thermo Fisher Scientific IFNAR1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human IFNAR1 (Interferon α/β/ω receptor 1). Suitable for WB and IP applications. Liquid form, unconjugated, 1 mg/mL concentration. Stored at 4°C and shipped on wet ice for research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 507–557 of human Interferon (α, β, ω) Receptor 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
Interferons are widely used therapeutic agents because of their antitumor and antiviral effects and their modulatory effects on the immune system (Biron, 2001; Kirkwood, 2002). These cytokines produce their effects by binding to the Type I Interferon Receptor (IFNAR1).
Down-regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down-regulation is thought to be influenced by phosphorylation of Serine 535 and 539 in IFNAR1 (Kumar et al., 2003).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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