Thermo Fisher Scientific H4K8ac Polyclonal Antibody
Rabbit polyclonal antibody recognizing acetylated histone H4K8 (H4K8ac). Validated for WB, ELISA, and Dot blot applications. Suitable for human samples. Provided in liquid form, unconjugated, stored at -20°C with sodium azide preservative.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:250 |
| ELISA | 1:500 |
| Dot Blot (DB) | 1:20,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Raised against histone H4 containing the acetylated lysine 8 (H4K8ac), using a KLH-conjugated synthetic peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Dry ice |
| RRID | AB_2533872 |
Target Information
Histones are basic nuclear proteins that form the nucleosome structure of chromosomal fiber in eukaryotes. Two molecules of each core histone (H2A, H2B, H3, and H4) form an octamer around which approximately 146 bp of DNA wraps, forming nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes, contributing to chromatin compaction.
This gene encodes a member of the histone H4 family, located in the large histone gene cluster on chromosome 6. Transcripts from this gene lack polyA tails but contain a palindromic termination element.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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