Thermo Fisher Scientific HLA Class 1 ABC (MHC I) Recombinant Rabbit Monoclonal Antibody (MHC-I/8366R)
HLA Class I (ABC, MHC I) 항원을 인식하는 Thermo Fisher Scientific의 재조합 Rabbit Monoclonal 항체입니다. 인간 시료에 반응하며 IHC(P), IHC(PFA) 등 다양한 면역조직화학 분석에 사용됩니다. 고순도 Protein A/G 정제 및 안정적인 액상 제형으로 제공됩니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | MHC-I/8366R |
| Immunogen | Recombinant fragment (around aa100–300) of human HLA-I protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus playing a crucial role in antiviral and antitumor defense. Human HLA-class I antigens are represented by HLA-A, HLA-B, and HLA-C molecules.
HLA and MHC antibodies are significant in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem mass spectrometry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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