Thermo Fisher Scientific NR0B2 Monoclonal Antibody (OTI6D8), TrueMAB
NR0B2 단백질을 인식하는 Mouse Monoclonal Antibody (Clone OTI6D8). Western blot에 적합하며, Human 시료에 반응. 고순도의 Affinity chromatography 정제 항체로, PBS/BSA/glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6D8 |
| Immunogen | Full length human recombinant protein of NR0B2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is an orphan receptor containing a putative ligand-binding domain but lacking a conventional DNA-binding domain. It belongs to the nuclear hormone receptor family, which includes transcription factors regulated by small hydrophobic hormones. Some members, including NR0B2, are orphan receptors with no known ligands. The protein interacts with retinoid, thyroid, and estrogen receptors, inhibiting their ligand-dependent transcriptional activation. It represses nuclear hormone receptor-mediated transactivation through competition with coactivators and direct transcriptional repressor functions.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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