Thermo Fisher Scientific UBE2B Recombinant Rabbit Monoclonal Antibody (JE56-12)
Recombinant Rabbit Monoclonal Antibody targeting UBE2B for WB and IHC applications. Reacts with human and zebrafish. High purity, Protein A purified, 1 mg/mL concentration. Ideal for studying ubiquitination and DNA damage repair mechanisms.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
- Publications: References
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Zebrafish |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JE56-12 |
| Immunogen | Synthetic peptide within N-terminal Human UBE2B (UniProt ID: P63146-1, Antigen Range: 1–152) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2911631 |
Product Specific Information
- Positive Control: A431 cell lysate, THP-1 cell lysate, HepG2 cell lysate, zebrafish tissue lysates, human breast carcinoma tissue, human fetal skeletal muscle tissue
- Subcellular Location: Nucleus, Cell membrane
Target Information
The modification of proteins with ubiquitin is an essential cellular process for degrading abnormal or short-lived proteins. Ubiquitination involves three enzyme classes: E1 (ubiquitin-activating), E2 (ubiquitin-conjugating), and E3 (ubiquitin-protein ligases). UBE2B belongs to the E2 ubiquitin-conjugating enzyme family and is required for post-replicative DNA damage repair. Its protein sequence is 100% identical among mouse, rat, and rabbit homologs, indicating strong conservation across eukaryotic evolution.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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