Thermo Fisher Scientific SRY Polyclonal Antibody
SRY 단백질을 인식하는 Rabbit Polyclonal Antibody로, 인간 및 랫트 시료에 반응합니다. Western blot, IHC, ICC/IF 등 다양한 응용에 적합하며, Affinity chromatography로 정제된 고품질 항체입니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human SRY (Accession Q05066), corresponding to amino acid residues V60–F110 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850591 |
Product Specific Information
Antibody detects endogenous levels of total SRY.
Target Information
This intronless gene encodes a transcription factor that belongs to the high mobility group (HMG)-box family of DNA-binding proteins. It acts as the testis-determining factor (TDF), initiating male sex determination. Mutations in this gene can result in XY females with gonadal dysgenesis (Swyer syndrome), while translocation of part of the Y chromosome containing this gene to the X chromosome can cause XX male syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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