Thermo Fisher Scientific SIRT2 Polyclonal Antibody
SIRT2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC에 적합. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 형태. 2–8°C 보관, 장기 보관 시 -20°C 권장.
- 카탈로그번호
- PA520490
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific SIRT2 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2.5–5 µg/mL |
| Immunohistochemistry (IHC) | 2.5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 17 amino acid peptide near the amino terminus of the human SIRT2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152520 |
Product Specific Information
- Suggested positive control: human brain tissue lysate
- PA5-20490 can be used with blocking peptide PEP-0610
Target Information
SIRT2 (Sirtuin for Silent Mating Type Information 2-Homolog) is a NAD-dependent deacetylase (NDAC) involved in gene silencing, cell cycle control, and DNA damage repair. It may act as a tumor suppressor in human gliomas and serve as a molecular marker for these cells. SIRT2 also functions as a redox sensor regulating muscle gene expression in response to food intake and exercise. It is phosphorylated in late G2 phase, M phase, and cytokinesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-20490_SIRT2_Q8IXJ6-1_Rabbit.svg)
(이미지: PA5-20490_SIRT2_Q8IXJ6-1_Rabbit_PDP.jpeg)
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