Thermo Fisher Scientific LGI2 Polyclonal Antibody
LGI2 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot에 적합. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제된 액상 형태, PBS 버퍼 및 sodium azide 포함. 연구용으로만 사용.
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Applications
- Western Blot (WB): Tested dilution 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 11 amino acid peptide from near the amino terminus of human LGI2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152470 |
Product Specific Information
- Suggested positive control: 293 cell lysate
- PA5-20492 can be used with blocking peptide PEP-0612
Target Information
The leucine-rich, glioma inactivated gene 2 (LGI2) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four highly related proteins containing leucine-rich repeats (LRRs), similar to other transmembrane signaling molecules and receptors.
LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), characterized by focal seizures with auditory symptoms.
Despite its high homology with LGI1 and similar expression pattern, mutations in LGI2 have not been found to be associated with ADTLE.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-20492_LGI2_Q8N0V4-1_Rabbit.svg, PA5-20492_LGI2_Q8N0V4-1_Rabbit_PDP.jpeg)
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