Thermo Fisher Scientific TIMP2 Monoclonal Antibody (T2-101)
TIMP2 단백질을 표적으로 하는 Mouse IgG1 단클론 항체로, Western blot 및 Immunoprecipitation에 적합. 인간 및 생쥐 시료에 반응하며, Protein G로 정제된 액상 형태. 4°C 보관, 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | View 3 publications |
| Immunocytochemistry (ICC/IF) | – | View 1 publication |
| Immunoprecipitation (IP) | 2 µg/mg protein lysate | View publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | T2-101 |
| Immunogen | Native human pro-MMP-2/TIMP-2 complex purified from A2058 culture medium followed by purified human rTIMP-2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11003336 |
Product Specific Information
MA5-13603 targets TIMP-2 in Immunoprecipitation and Western blot applications and shows reactivity with Human samples.
The MA5-13603 immunogen is native human pro-MMP-2/TIMP-2 complex purified from A2058 culture medium followed by purified human rTIMP-2.
Target Information
TIMP-1 and TIMP-2 are inhibitory enzymes of the matrix metalloproteinase family, and are important for maintaining connective tissue integrity.
TIMP-2 shows high binding affinity to both latent (pro) and active forms of 72 kDa Type IV collagenase (MMP-2 or gelatinase A), and also binds the active form of 92 kDa Type IV collagenase (MMP-9 or gelatinase B).
TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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