Thermo Fisher Scientific alpha-2c Adrenergic Receptor Monoclonal Antibody (N330A/80), PE
Alpha-2C 아드레날린 수용체를 검출하는 Thermo Fisher Scientific의 단클론 항체로, PE 형광 표지된 Mouse IgG1 형입니다. Western blot 및 ICC/IF에 사용 가능하며, 높은 특이성과 재현성을 제공합니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N330A/80 |
| Immunogen | Synthetic peptide amino acids 442–462 (QDFRRSFKHILFRRRRRGFRQ, cytoplasmic C-terminus) of human Alpha-2C adrenergic receptor |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932072 |
Additional Formats
- Unconjugated: MA5-27724
- APC: MA5-45615
- FITC: MA5-45616
- PerCP: MA5-45617
- Custom conjugation available upon request
Product Specific Information
- 1 µg/mL of MA5-45618 detects Alpha-2C Adrenergic Receptor in 20 µg of COS cells transiently transfected with HA-tagged Alpha lysate by colorimetric immunoblot using goat anti-mouse IgG:HRP as secondary antibody.
- Detects 50 kDa or larger (possibly due to dimerization).
- Does not cross-react with other adrenergic receptors.
- Formerly sold as clone S330A-80.
Target Information
Alpha-2-adrenergic receptors are G protein-coupled receptors with three subtypes: alpha2A, alpha2B, and alpha2C.
They regulate neurotransmitter release from sympathetic nerves and adrenergic neurons in the CNS.
Mouse studies show both alpha2A and alpha2C are required for normal presynaptic control of transmitter release.
The alpha2A subtype inhibits release at high stimulation frequencies, while alpha2C modulates neurotransmission at lower activity levels.
This gene encodes the alpha2C subtype, containing no introns in either coding or untranslated regions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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