Thermo Fisher Scientific CDC25a Polyclonal Antibody
Rabbit polyclonal antibody recognizing human CDC25a. Validated for WB and IP applications. Affinity purified and supplied as a liquid at 1 mg/mL. Recommended storage at 4°C. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,500 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 175 and 225 of human Cell Division Cycle 25A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
CDC25a is a member of the CDC25 family of phosphatases. Three CDC25 genes are present in human cells: CDC25A, CDC25B, and CDC25C. These genes function at different phases of the cell cycle.
CDC25a is required for progression through G1 and S phases and activates the cyclin-dependent kinase CDC2 by removing two phosphate groups.
CDC25A is specifically degraded in response to DNA damage, preventing cells with chromosomal abnormalities from dividing.
CDC25A is an oncogene, although its exact role in oncogenesis has not been fully demonstrated.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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