Thermo Fisher Scientific S100A10 Polyclonal Antibody
S100A10 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody로, Western blot, IHC, ICC, Flow cytometry 등 다양한 응용에 적합합니다. 고순도의 친화 크로마토그래피 정제 제품으로, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL | 5 publications |
| Immunohistochemistry (IHC) | – | 6 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–5 µg/mL | 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | – | 1 publication |
| Immunocytochemistry (ICC/IF) | 5 µg/mL | 3 publications |
| Flow Cytometry (Flow) | 1–3 µg/1×10⁶ cells | 1 publication |
| ELISA | 0.1–0.5 µg/mL | – |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived human S100A10 recombinant protein (Position: Q4–K94) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 4 mg trehalose |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2807307 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
The S-100 family of calcium-activated proteins interact with a range of target proteins to modulate biological signaling pathways. Numerous cancer cell lines overexpress the plasminogen receptor S-100A10 on the extracellular cell surface, where it forms a heterotetrameric complex with Annexin II, though this association is not required for plasma membrane localization or binding and activation of plasminogen. Additionally, S-100A10 acts as a cellular chaperone for hepatitis B virus polymerase, influencing its nuclear localization and suggesting a role in viral replication.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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