Thermo Fisher Scientific LMTK2 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

Antibody detects endogenous levels of total LMTK2.

Target Information

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the γ phosphate of ATP, onto an acceptor amino acid in a substrate protein. Through this mechanism, protein kinases mediate most signal transduction in eukaryotic cells, regulating metabolism, transcription, cell cycle progression, cytoskeletal rearrangement, cell movement, apoptosis, and differentiation.
The protein kinase family, with more than 500 gene products, is one of the largest in eukaryotes and is classified into 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
The tyrosine kinase (TK) group primarily regulates cell-cell interactions such as differentiation, adhesion, motility, and death. Approximately 90 TK genes have been sequenced, including 58 receptor protein TKs (e.g., EGFR, EPH, FGFR, PDGFR, TRK, VEGFR) and 32 cytosolic TKs (e.g., ABL, FAK, JAK, SRC).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.