Thermo Fisher Scientific HSP60 Monoclonal Antibody (4B9/89), Alexa Fluor 647

Thermo Fisher Scientific HSP60 Monoclonal Antibody (4B9/89), Alexa Fluor 647

Applications

• Western Blot (WB)
  Tested Dilution: Not specified
  View 1 publication

• Immunocytochemistry (ICC/IF)
  Tested Dilution: 1–10 µg/mL
  View references

Product Specifications

Additional Formats

• Unconjugated
• Alexa Fluor 488
• Alexa Fluor 555
• Request custom conjugation

Product Specific Information

The MA3012A647 antigen is human placental HSP60.
Epitope mapping studies using human HSP60 deletion mutants suggest that this antibody binds either between amino acids 335–366 or 484–547.

Target Information

This gene encodes a member of the chaperonin family.
The encoded mitochondrial protein may function as a signaling molecule in the innate immune system and is essential for the folding and assembly of newly imported proteins in the mitochondria.
This gene is adjacent to a related family member, and the region between the two genes functions as a bidirectional promoter.
Several pseudogenes have been associated with this gene.
Two transcript variants encoding the same protein have been identified.
Mutations in this gene cause autosomal recessive spastic paraplegia 13.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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