Thermo Fisher Scientific IL-12 p35 Polyclonal Antibody
IL-12 p35 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. 인간, 마우스, 랫트에 반응하며 IHC(P)에서 1:50~1:200 희석으로 사용됩니다. 고순도(>95%) 항체로 PBS/glycerol 완충액에 보관되며 연구용으로 적합합니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 32–81 of Human IL-12A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2803340 |
Product Specific Information
- Purity is >95% by SDS-PAGE.
Target Information
Interleukin 12A (IL-12A) is a signaling cytokine in the Interleukin-6 superfamily. The IL-12 alpha chain precursor (p35) forms a 35-kD subunit of the IL-12 heterodimer and exhibits diverse biological activities. IL-12A functions as a growth factor for activated T and NK cells, enhances NK cell cytolytic activity, and stimulates IFN-gamma production. It contributes to Th1 and Th2 differentiation and regulates Stat4 phosphorylation. IL-12A also participates in innate immune signaling requiring nitric oxide synthase 2A. Together with EBI3, IL-12A forms interleukin-35 (IL-35), a cytokine produced by regulatory T cells with suppressive functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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