Thermo Fisher Scientific CD51 Polyclonal Antibody
CD51(Integrin αV) 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P) 실험에 적합. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제되었으며, 고순도(>95%) 보장. 연구용으로만 사용 가능.
- 카탈로그번호
- PA586575
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 771–820 of Human Integrin alphaV |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2803345 |
Product Specific Information
- Purity is >95% by SDS-PAGE.
Target Information
ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains that combine with multiple integrin beta chains to form different integrins.
Among the known associating beta chains (β1, β3, β5, β6, and β8; ITGB1, ITGB3, ITGB5, ITGB6, ITGB8), each can interact with extracellular matrix ligands. The αVβ3 integrin, known as the Vitronectin Receptor (VNR), is one of the most studied.
In addition to adhesion, many integrins facilitate signal transduction. The ITGB3 gene encodes the integrin beta chain β3, which forms a complex with the αIIb chain in platelets. Integrins participate in cell adhesion and cell-surface mediated signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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