Thermo Fisher Scientific EGFR (E746-A750del) Recombinant Rabbit Monoclonal Antibody (HL363)
EGFR(E746-A750del) 변이 단백질을 특이적으로 인식하는 Thermo Fisher의 재조합 토끼 단클론 항체. Western blot에 최적화되어 있으며, 고순도 Protein A 정제 및 PBS 완충액에 보존. 연구용으로 폐암 관련 EGFR 변이 분석에 적합.
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Applications and Tested Dilution
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HL363 |
| Immunogen | Human EGFR (E746-A750del) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911498 |
Product Specific Information
Store as a concentrated solution. Centrifuge briefly prior to opening vial.
For short-term storage (1–2 weeks), store at 4°C.
For long-term storage, aliquot and store at -20°C or below.
Avoid multiple freeze-thaw cycles.
Target Information
The protein encoded by this gene is a transmembrane glycoprotein and a member of the protein kinase superfamily.
It acts as a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor; binding induces receptor dimerization and tyrosine autophosphorylation, leading to cell proliferation.
Mutations in this gene are associated with lung cancer.
[provided by RefSeq, Jun 2016]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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