Thermo Fisher Scientific VNN3 Polyclonal Antibody
Western blot과 IHC에 모두 사용 가능한 Rabbit Polyclonal 항체로, Human, Mouse, Rat에 반응합니다. 항원 친화 크로마토그래피로 정제되었으며 PBS buffer에 0.02% sodium azide를 포함합니다. VNN3 단백질 연구용으로 적합합니다.
- 카탈로그번호
- PA534459
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 19 amino acid synthetic peptide near the carboxy terminus of human VNN3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551811 |
Product Specific Information
A suggested positive control is human brain tissue lysate.
PA5-34459 can be used with blocking peptide PEP-1501.
Target Information
The vanin family is a novel group of ectoenzymes that function in tissue repair and play a role in oxidative-stress response. As both secreted and membrane proteins, the vanin family members have been implicated as therapeutic targets in inflammatory disease.
VNN3 (vascular non-inflammatory molecule 3), also known as Vanin3, is a 501 amino acid GPI-anchored amidohydrolase that is widely expressed and found at highest levels in blood and liver. Induced by Th17/Th1 type cytokines, VNN3 converts pantetheine into pantothenic acid. Containing one CN hydrolase domain, VNN3 is encoded by a gene that maps to human chromosome 6q23.2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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