Thermo Fisher Scientific TNFAIP8L2 Recombinant Rabbit Monoclonal Antibody (19H35L22)

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

1:100

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Expression System

Expi293

Class

Recombinant Monoclonal

Type

Antibody

Clone

19H35L22

Immunogen

Protein corresponding to human TNFAIP8L2 [aa45-aa184] if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TNFAIP8L2,uniProtId:Q6P589-1,ncbiNodeId:9606,antigenRange:45-184,antigenLength:184,antigenImageFileName:703165_TNFAIP8L2_Q6P589-1_Rabbit.svg,antigenImageFileNamePDP:703165_TNFAIP8L2_Q6P589-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2784566

Product Specific Information

This antibody is predicted to react with Human, Mouse, Monkey, Pig, Horse, Cat.

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Target Information

TNFAIP8L2 - Tumor necrosis factor alpha-induced protein 8-like protein 2 (also known as TIPE2) acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. It is a negative regulator of Toll-like receptor and T-cell receptor functions. TIPE2 prevents hyperresponsiveness of the immune system and maintains immune homeostasis. It inhibits JUN/AP1 and NF-kappa-B activation. TIPE2 also promotes Fas-induced apoptosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.