Thermo Fisher Scientific MYCN Monoclonal Antibody (PCRP-MYCN-1A9)

Applications

Tested Dilution

Publications

Flow Cytometry (Flow)

1-2 µg/mL

-

ELISA (ELISA)

2-4 µg/mL

-

Peptide Array (Array)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

PCRP-MYCN-1A9

Immunogen

Recombinant protein domain (around aa335-463) of human MYCN protein if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:n-Myc,uniProtId:P04198-1,ncbiNodeId:9606,antigenRange:335-463,antigenLength:464,antigenImageFileName:4613-MSM2-P0_n-Myc_P04198-1_House_mouse.svg,antigenImageFileNamePDP:4613-MSM2-P0_n-Myc_P04198-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

200 µg/mL

Purification

Protein A/G

Storage buffer

PBS with 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Positive Control:293T whole cell lysates or recombinant Human n-Myc protein.

Cellular Location: Nucleus.

Target Information

N-Myc protein is member of the MYC family of transcription factor proteins with a basic helix-loop-helix (bHLH) domain. N-Myc is similarly regulated and functionally complementary to C-Myc in the context of various cellular growth and differentiation processes. MYCN gene is considered the hallmark of neuroblastoma, amplification and overexpression of the MYCN proto-oncogene occurs in approximately 20% of neuroblastomas and is associated with advanced stage disease, rapid tumor progression, and poor prognosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.